Can/should you take these long term? Is it ok to split them up with meals throughout the day or are they more effective taken all at once?

The dosage is 1 packet one time per day. You may want to consult your health care practitioner regarding the duration of use.

Does this take the place of a multi vitamin?

Detox Pure Pack contains 3 capsules of Ultra Nutrient multivitamin/mineral complex. We recommend consulting with your healthcare practitioner to determine if an additional multivitamin is needed.

It says phase ii in the description, what is phase i?

The liver functions in two phases to transform toxins so they can be eliminated from the body. Each phase relies on specific nutrients for optimal performance, with phase one setting the stage for how well the liver performs during phase two. The two phases depend on different nutrients and must be in balance with one another to function optimally. Phase I enzymes begin the detoxification process by chemically transforming fat-soluble compounds into water-soluble compounds. Water-soluble compounds can easily be excreted, while fat-soluble compounds can be stored in fat cells, where they are protected from the body’s detoxification enzymes.

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