An Introduction to Medicinal Chemistry

I have never written a review before but this book has become a fixture in my life. It has become dog eared, marked up, highlighted, underlined - the works. To put this in perspective, I have a background and degree in computer science and am in a PhD program doing computational drug design. I had enough undergrad premed to be dangerous and to follow discussions, but my true strength was on the computational side. I bought this book to help me pick up my chemistry and biochemistry and, with all due humility, it worked like a charm. The explanations are clear and beautiful and, if you like this stuff, it's a page turner. Seriously. Yes, it is an introductory text. But man is it a good one. From here I have been able to move on to other graduate texts, contribute equally in my lab on the biochem front, and even had the opportunity to ask some questions of Christopher Lipinski (of Rule of Five fame) at a conference without embarrassing myself. If you are relatively new to drug design or medicinal chemistry or pharmacology and want to come up to speed quickly, and have at least, say, AP high school chemistry or maybe undergrad chemistry, particularly with at least one organic chem class, BUY THIS BOOK. I cannot say it enough. If you are in a position similar to mine, this book is outstanding. In the context of my degree program, maybe even life changing. The single best academic purchase I've made. Sorry to come off like a fan boy, but this book earned it. It's that good.

Just a heads up, if you have not taken at least a semester of organic chemistry and preferably a little biochem, this book is going to be way over your head. But if you’ve taken organic chemistry and know some basic biochem you will love this book. It is laid out beautifully and the illustrations are clear and informative. After each section there is a bullet pointed review of what you just read, a very nice feature! I am about halfway through it now and I must say I have been very impressed! If you want to go into pharmaceutical R &D, this book is a must read!

I believe this textbook is priced fairly. There is a lot of information, helpful graphics, and good organization. One of the few physical textbooks I bothered purchasing outright rather than borrowing or purchasing used.

over all satisfied with the condition of the book and it matched what was promised.

Bought the third edition for a class and I didnt even need this one but since I read the last edition I knew this would be good as well. So far I have not been disappointed and there is a good deal of information that was not in the last edition. This book is highly recommended.

The book was really helpful for my class

A very useful text for pharmacy students who are learning medicinal chemistry.

Thanks so much.