---
product_id: 10276193
title: "K9 Advantix II Extra Large Dog"
brand: "k9 advantix"
price: "E£ 9539"
currency: EGP
in_stock: true
reviews_count: 10
category: "K9 Advantix"
url: https://www.desertcart.com.eg/products/10276193-k9-advantix-ii-extra-large-dog
store_origin: EG
region: Egypt
---

# For dogs 55+ lbs Waterproof after 24 hours Kills fleas in 12 hours K9 Advantix II Extra Large Dog

**Brand:** k9 advantix
**Price:** E£ 9539
**Availability:** ✅ In Stock

## Summary

> 🐾 Protect your big pup like a pro—fast, fuss-free, and foolproof!

## Quick Answers

- **What is this?** K9 Advantix II Extra Large Dog by k9 advantix
- **How much does it cost?** E£ 9539 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.com.eg](https://www.desertcart.com.eg/products/10276193-k9-advantix-ii-extra-large-dog)

## Best For

- k9 advantix enthusiasts

## Why This Product

- Trusted k9 advantix brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Effortless Application:** Fragrance-free, topical treatment that’s quick, mess-free, and waterproof after 24 hours
- • **No Prescription Needed:** Convenient OTC availability means no vet visit required—stock up and never miss a dose
- • **Rapid Flea Elimination:** Kills fleas within 12 hours to stop infestations fast
- • **All-in-One Pest Defense:** Vet-recommended formula repels & kills fleas, ticks, mosquitoes, biting flies, and lice
- • **Tailored for Large Dogs:** Specifically designed for dogs over 55 lbs, ensuring optimal dosage and protection

## Overview

K9 Advantix II XL is a vet-recommended, topical flea, tick, mosquito, biting fly, and lice treatment designed for dogs over 55 lbs. It kills fleas within 12 hours and provides waterproof protection after 24 hours. This fragrance-free formula repels pests on contact, preventing bites and infestations without the need for a prescription. Available in convenient multi-dose packs, it offers reliable monthly defense for your large dog’s outdoor and indoor adventures.

## Description

K9 Advantix II Extra Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Extra Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh over 55 lbs. to use K9 Advantix II Extra Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Extra Large Dog is a trademark of Elanco or its affiliates.

Review: Reliable product - highly recommend - works !!! - Always use this brand flea preventative . It kills many critters trying to annoy and hurt my pups . I want my fur covers kids just as safe as my flesh covered kids ;) The product is the best for fleas ticks and mosquitos . And in this heat and lack of freezing temps , ticks and rad and skeeters are running ramped out there . The size depends on your dog’s weight please read their chart within the ad . Then there are single dose , 2 pack, 3 pack and 6 packs available . It is to be used once a month . Imagine this .. the liquid seeps into your pets skin and spreads around via the oil in the skin . It gives them complete protection as far as coverage . There is not a spot a flea can bite them and survive . Most fleas and ticks will be repelled by the scent that we cannot smell once it is “ in/ on “ them . It uses your pets natural body chemistry to help it work better . You should wait at least 2 days after giving a bath to use flea protection like this . The pet needs to replenish the oils that a bath(shampoos) dries out . Then it will work better . Do not use on wet skin either . It is best to separate the hairs on your let until you see skin ( best spot usually base of back of neck where they cannot reach or lick it ) Then place the vial to the skin and squeeze gently . Be aware of your eyes !! If you have larger dogs there is more in the vial so I will do one spot then spread hairs next to that spot and apply rest in same area but different spot This way it all sinks in and it won’t run onto the hair and clump up . If it does leave it for now let it all dry after a day just brush the spot to eliminate a tangle . I have been using this product for as long as I can remember and the animal hospital I worked at recommend this product as well . It will treat more than frontline plus will . I feel better also. My dogs don’t itch all the time . There have been no reactions or issues from this product on their skin . IF ingested by pet they need to be taken to ER right away . And if ingested by humans as well-ER move it move it move it !!! Poisonous if ingested or gets into eyes of you or pet. I like the snap open vial better than the get scissors and cut open vial Doing that can cause a squirt . I always look other way when opening these and never near pets face . Always wash hands with damp after applying to pet asap. A very durable reliable product for your and your babies . A size for every pet and peace of mind for every owner / parent
Review: My go to for Flea and tick prevention. - After trying several different flea and tick treatments over the years, K9 Advantix has consistently been one of the most effective options for my dog. Application is quick and straightforward, and within a short time I noticed a significant reduction in fleas. Living in an area where ticks are common, it’s reassuring to know my dog has reliable protection during walks, hikes, and time spent outdoors. One thing I appreciate is that it doesn’t leave a heavy, greasy residue once it’s had time to dry, and my dog hasn’t shown any signs of irritation after application. Following the recommended dosing schedule has kept the protection consistent month after month. The peace of mind alone makes it worth the investment. Keeping fleas and ticks under control is much easier than dealing with an infestation, and this product has helped do exactly that. Based on my experience, K9 Advantix is a dependable choice for pet owners looking for effective, easy-to-use flea and tick protection.

## Features

- K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
- Kills fleas within 12 hours of application
- Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
- Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
- No prescription needed

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B004QREOPU |
| Active Ingredients | Imidacloprid, Permethrin, Pyriproxyfen |
| Age Range Description | 7 weeks and older |
| Allergen Information | Allergen-Free |
| Best Sellers Rank | #200 in Pet Supplies ( See Top 100 in Pet Supplies ) #2 in Dog Flea Drops |
| Brand | K9 Advantix |
| Brand Name | K9 Advantix |
| Customer Reviews | 4.5 out of 5 stars 49,343 Reviews |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00724089204103 |
| Included Components | 4 |
| Item Form | Topical |
| Item Type Name | Topical |
| Item Volume | 16 ml |
| Item Weight | 1.6 ounces |
| Manufacturer | Elanco US Inc |
| Manufacturer Part Number | 86315017 |
| Model Number | 86315017 |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 724089204103 |
| Unit Count | 4 Count |
| Volume | 16 ml |
| Warranty Description | No_warranty |

## Product Details

- **Active Ingredients:** Imidacloprid, Permethrin, Pyriproxyfen
- **Allergen Information:** Allergen-Free
- **Brand:** K9 Advantix
- **Color:** Extra-Large Dog only
- **Dog Breed Size:** Large
- **Item Form:** Topical
- **Item Volume:** 16 ml
- **Item Weight:** 1.6 ounces
- **Scent:** Unscented
- **Unit Count:** 4 Count

## Images

![K9 Advantix II Extra Large Dog - Image 1](https://m.media-amazon.com/images/I/71cpzdT1OpL.jpg)
![K9 Advantix II Extra Large Dog - Image 2](https://m.media-amazon.com/images/I/91j1gzP2vFL.jpg)
![K9 Advantix II Extra Large Dog - Image 3](https://m.media-amazon.com/images/I/81EDjQqM2WL.jpg)
![K9 Advantix II Extra Large Dog - Image 4](https://m.media-amazon.com/images/I/81lc7ZPFGHL.jpg)
![K9 Advantix II Extra Large Dog - Image 5](https://m.media-amazon.com/images/I/71tUbLQ4DWL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: Has anyone switched over from Frontline Plus to K9 Advantix II and is happy? For Dogs**
A: YES!!!!  I've had the same experience with my dogs as Nicole A replied.  I had been pleased with Frontline for years....but in 2012 (and ever since) it has just stopped working.  One of my dogs is a fur-making machine: and fleas don't seem to bother him...even if I am finding them on him.  The other dog has horrible flea allergies:  has immediate, sustained, and severe "hot spots" after even just ONE flea bite...skin will turn pink all over his body...and he "blows" large amounts of his beautiful, lush, scruffy coat...and he just doesn't seem to be his usual happy, bright, and enthusiastic self :-(   Using Advantix II....he seems to not have problems at all (it keeps the fleas from breeding...although if one occasional transient flea bites him....it will die...but the dog will still get a "hotspot", but nowhere as intense or sustained as without Advantix II...and if I find it quickly and clean it with vinegar, he may not even need a dose of benedryl).  During the "flea season" since using Advantix II he has been able to keep his lush coat with no problems.....to such an extent that I brought him in to my vet's office just to show the vet how well he was doing one summer (the dog had been so bad the previous summer while using Frontline that I had to take him to the vet for skin reactions, fur loss in large areas of his coat, and a secondary infection from scratching...I had been so discouraged about the flea problems that year while on Frontline that I had been taking the dog daily to the lake so he could swim and drown the damned fleas).  The vet was very pleased with the dog's condition with Advantix II, and had stated he has learned from his patients that they are also seeing less effectiveness with Frontline in recent years.  I won't use anything else but Advantix II during this up-coming flea season.  (although I do also spray his coat/skin with vinegar (mixed 1/2 with water) each day as a flea deterrent...especially if he gets a hotspot...and I add a small amount of vinegar to his food as well........and when he does need a bath:  I use EXTREMELY diluted Dr. Bronner's castile liquid soap in the "EUCALYPTUS" version....the dog tolerates it well...and it seems the scent repels fleas a bit.   I use the soap as well to launder the cover of his dog bed at least weekly).   I know that insects can get resistent to certain pesticides over time....and I suspect that is why Frontline no longer works in our area.....I sure hope it doesn't eventually happen with Advantix II as well....and I hope that producers of flea/tick products for dogs will monitor this situation and re-formulate their products as needed to address the situation--regionally if need be.

**Q: I thought I was ordering Advantage II but by mistake, ordered Advantix II.  What is the difference, and does it work the same?**
A: You can’t use advantix on cats.  sadly because advantix 2 is superior and is the best out there because unlike advantage (and unlike frontline) it repels flies and mosquitoes as well as ticks and fleas.  but it is toxic to cats.  as cats should be indoors only you shouldn’t need tick/mosquito repellent just flea.  DO NOT USE ADVANTIX ON CATS!  It is toxic to them

**Q: What about cats? I used to use Advantix on my cats with no problems, as suggested by my vet to save money. Has the formula changed?**
A: Look at the active ingredients for both the dog & cat formulas; They are exactly the same. Only difference is the dosage size which you can easily look up on the internet & save yourself a ton of money

**Q: Could I use this along with a flea/tick collar?**
A: As a vet tech we say a flea collar is basically worthless..At most may keep fleas off pets head. If you can buy flea collar at store probably won’t work and even the script only work minimal. Stick to topical like frontline plus, advantage, advantix and oral like Capstar. Flea collars are most always a waste of $. To remove fleas fast simply bathe dog and let dog sit in water…drowning fleas and follow up in few hours with topical if bad infestation. Just a flea or 2 I’d still bathe but topical probably enough. All topicals are water resistant after 24hr

## Customer Reviews

### ⭐⭐⭐⭐⭐ Reliable product - highly recommend - works !!!
*by S***J on August 5, 2026*

Always use this brand flea preventative . It kills many critters trying to annoy and hurt my pups . I want my fur covers kids just as safe as my flesh covered kids ;) The product is the best for fleas ticks and mosquitos . And in this heat and lack of freezing temps , ticks and rad and skeeters are running ramped out there . The size depends on your dog’s weight please read their chart within the ad . Then there are single dose , 2 pack, 3 pack and 6 packs available . It is to be used once a month . Imagine this .. the liquid seeps into your pets skin and spreads around via the oil in the skin . It gives them complete protection as far as coverage . There is not a spot a flea can bite them and survive . Most fleas and ticks will be repelled by the scent that we cannot smell once it is “ in/ on “ them . It uses your pets natural body chemistry to help it work better . You should wait at least 2 days after giving a bath to use flea protection like this . The pet needs to replenish the oils that a bath(shampoos) dries out . Then it will work better . Do not use on wet skin either . It is best to separate the hairs on your let until you see skin ( best spot usually base of back of neck where they cannot reach or lick it ) Then place the vial to the skin and squeeze gently . Be aware of your eyes !! If you have larger dogs there is more in the vial so I will do one spot then spread hairs next to that spot and apply rest in same area but different spot This way it all sinks in and it won’t run onto the hair and clump up . If it does leave it for now let it all dry after a day just brush the spot to eliminate a tangle . I have been using this product for as long as I can remember and the animal hospital I worked at recommend this product as well . It will treat more than frontline plus will . I feel better also. My dogs don’t itch all the time . There have been no reactions or issues from this product on their skin . IF ingested by pet they need to be taken to ER right away . And if ingested by humans as well-ER move it move it move it !!! Poisonous if ingested or gets into eyes of you or pet. I like the snap open vial better than the get scissors and cut open vial Doing that can cause a squirt . I always look other way when opening these and never near pets face . Always wash hands with damp after applying to pet asap. A very durable reliable product for your and your babies . A size for every pet and peace of mind for every owner / parent

### ⭐⭐⭐⭐⭐ My go to for Flea and tick prevention.
*by R***N on July 9, 2026*

After trying several different flea and tick treatments over the years, K9 Advantix has consistently been one of the most effective options for my dog. Application is quick and straightforward, and within a short time I noticed a significant reduction in fleas. Living in an area where ticks are common, it’s reassuring to know my dog has reliable protection during walks, hikes, and time spent outdoors. One thing I appreciate is that it doesn’t leave a heavy, greasy residue once it’s had time to dry, and my dog hasn’t shown any signs of irritation after application. Following the recommended dosing schedule has kept the protection consistent month after month. The peace of mind alone makes it worth the investment. Keeping fleas and ticks under control is much easier than dealing with an infestation, and this product has helped do exactly that. Based on my experience, K9 Advantix is a dependable choice for pet owners looking for effective, easy-to-use flea and tick protection.

### ⭐⭐⭐⭐⭐ It works and works fantastically
*by Y***N on June 8, 2026*

I've been using K9 Advantix (I and II), and I've never had to worry about ticks, fleas or mosquitos, and I live out in the woods in a state that has these critters *everywhere*. My dogs walk all around in the fenced off area of ~4 acres, which I keep mowed to 3.5 inches and only a few trees in the main backyard but a .5 acre cedar grove in the front of the house. Cedar keeps the climbing bugs at bay well enough, but walking the fence line in the back and around the 100 yd x 50 yd pond and I have to check for ticks on me when I get in. The dogs will have a couple on them, but they never get the chance to dig in, so leaving them outside a lot of the day and night doesn't concern me. When they're inside, wherever they sit or lay, they're leaving an extremely small bit of this stuff on the material that also kills the crawling critters. The pond, naturally has mosquitos, but they don't hardly land on the dogs...unfortunately they DO land on me. As I said, I've used this stuff for decades on my dogs and because of it they're not uncomfortable from biting insects and the mosquitos pretty much leave them alone or die after lighting on them and don't infect them with heartworms. Also, this is like water, so when putting it on the dogs you need to put it in several spots on their back for it to work best. Because it's a water-type stuff, no more messy, gunky oil-based junk to get all over your hands or places they lie or collect dust/dirt/etc. Overall this can't be beat since it covers pretty much any critters that would love to make a home on your dog.

## Frequently Bought Together

- K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 4-Mo Supply
- K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply
- K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 4-Mo Supply

---

## Why Shop on Desertcart?

- 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016
- 🌍 **Shop Globally** — Access 737+ million products across 21 categories
- 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price
- 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members)
- 🔒 **Secure Payments** — Trusted payment options with buyer protection
- ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews

**Shop now:** [https://www.desertcart.com.eg/products/10276193-k9-advantix-ii-extra-large-dog](https://www.desertcart.com.eg/products/10276193-k9-advantix-ii-extra-large-dog)

---

*Product available on Desertcart Egypt*
*Store origin: EG*
*Last updated: 2026-09-07*