--- product_id: 59482166 title: "Nature's Trove SAM-e 400mg 120 Enteric Coated Caplets (2 Boxes of 60) - Vegan, Kosher, Non-GMO, Soy Free, Gluten Free - Mood and Joint Comfort - Cold Form Blister Packed" brand: "nature's trove" price: "E£ 9525" currency: EGP in_stock: true reviews_count: 11 category: "Nature's Trove" url: https://www.desertcart.com.eg/products/59482166-natures-trove-sam-e-400mg-120-enteric-coated-caplets-2 store_origin: EG region: Egypt --- # Vegan, Non-GMO, Gluten & Soy free 400mg potent SAM-e dose Enteric coated for max absorption Nature's Trove SAM-e 400mg 120 Enteric Coated Caplets (2 Boxes of 60) - Vegan, Kosher, Non-GMO, Soy Free, Gluten Free - Mood and Joint Comfort - Cold Form Blister Packed **Brand:** nature's trove **Price:** E£ 9525 **Availability:** ✅ In Stock ## Summary > 💼 Elevate your wellness game with Nature’s Trove SAM-e — because thriving is the new hustle. ## Quick Answers - **What is this?** Nature's Trove SAM-e 400mg 120 Enteric Coated Caplets (2 Boxes of 60) - Vegan, Kosher, Non-GMO, Soy Free, Gluten Free - Mood and Joint Comfort - Cold Form Blister Packed by nature's trove - **How much does it cost?** E£ 9525 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.com.eg](https://www.desertcart.com.eg/products/59482166-natures-trove-sam-e-400mg-120-enteric-coated-caplets-2) ## Best For - nature's trove enthusiasts ## Why This Product - Trusted nature's trove brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Freshness Sealed:** Cold form blister packaging locks in potency and freshness, so you never miss a dose. - • **Dual-Action Wellness:** Supports both mood enhancement and joint flexibility, empowering your active lifestyle. - • **Precision Absorption:** Enteric coating ensures SAM-e bypasses stomach acid, delivering maximum bioavailability where it counts. - • **Clean & Conscious Formula:** Vegan, kosher, non-GMO, soy and gluten-free—crafted for the mindful professional. - • **Clinically Backed Potency:** 400mg of pure SAM-e per caplet, scientifically optimized for mood and joint support. ## Overview Nature's Trove SAM-e 400mg caplets deliver a premium, scientifically formulated supplement designed to support mood, joint flexibility, and liver health. Featuring enteric-coated, vegan, kosher, and allergen-free caplets, this 120-count pack ensures optimal absorption and freshness, making it the go-to choice for health-conscious professionals seeking natural, effective daily support. ## Description Buy Nature's Trove SAM-e 400mg 120 Enteric Coated Caplets (2 Boxes of 60) - Vegan, Kosher, Non-GMO, Soy Free, Gluten Free - Mood and Joint Comfort - Cold Form Blister Packed on desertcart.com ✓ FREE SHIPPING on qualified orders Review: Fast and good source of nutritional supplements. - SAMe, S-adenyl L Methionine has been noted by research to improve cartilage formation. As you see from the name, it is essentially an amino acid. I purchased the 200 and 400 mg quantities. The product is a molecule that is synthesized by some yeasts - bakers' yeast is most common. While I cannot personally double-blind test its effectiveness, scientific evaluation has, and has shown it to increase cartilage recovery. I nearly completely re-tore a long-previously reconstructed knee , and, as my other knee had also been damaged by significant aerial mistakes and landings I sought more than just the usual chondroitin, MSM, etc. Having seen live images of the cartilage damage in my knees, and exploring the research, I strongly feel that SAMe is worth purchase. This brand is naturally-sourced - a good selling point, and it is reasonably priced on comparison to many others. SAMe is also sold as neuroactive, due to its part in the synthesis of serotonin, which was a matter of concern. Serotonin is synthesized through the production and synthesis of this molecule, in great part by mutualist symbiotic enteric microorganisms. Again, because this is natural, it is almost certainly a good nutritional supplement, as enteric organisms tend to change quickly in response to different dietary intake. Thus, it promotes more regular synthesis of one of the most important neurotransmitters. Due to the highly stressful period in which all of us are immersed, I haven't looked deeper into that neurological issue, although we DO know a few things about it. Serotonin itself cannot cross into the brain, and that produced in the intestines affects other physiological processes - we need it. But excess serotonin production in the brain affects males and females differently and the brain's feedback processes tend to act to restore normality (it's possible that some individuals may experience persistent insufficiency OR excess, but those are a small minority. .If you suspect such long-term problem, do consult a medical therapist - Psychologists can refer those with metabolic problems of persistent types to psychiatrists who can test for such problems. But recognize that serotonin understanding is in its infancy, and the past with its SSRIs and other quite invasive drugging, is like using a hammer to fix a computer board or a brain) That, in short, is why I do NOT recommend that people seek neurotropic drugs - from alcohol to other drugs, we interfere with or destroy natural functioning, which it's sometimes better to address ONLY through physical, mental, social activities. SAMe is, though, pretty much methionine, a food, and we may often be deficient in that amino acid - which is why it can improve cartilage formation, as well as other variables like digestion. So, explore the effects of ANYTHING you ingest, and DO NOT just take things because of inane claims unsupported by rigorous scientific research. This company was extremely responsive (FAST!) to my desertcart order, and, so, with its component sourcing, seems a great place from which to purchase nutritional products. While I have experienced reduced pain , I had also been expanding the exercise of joints I injured and reinjured, and so cannot honestly evaluate sensations like pain reduction for others. I use less aspirin since the combination of SAMe, the natural healing process, and slow increase of exercise of affected joints, and as usual recommend any safe reduction of NSAID use. SAMe does not have the deleterious side effects of NSAIDs. Review: Works great for fibromyalgia! - Great price and quality! ## Features - PREMIUM QUALITY: Nature's Trove is committed to making the highest quality SAM-e supplements affordable for all consumers. We start with raw material that contains the highest level of the active S.S. Isomer, and manufacture it under strictly controlled GMP conditions. The caplets are enteric coated for optimal absorption, and blister packaged for maximum freshness. Our product is free from allergens, artificial coloring and flavors; suitable for vegan, GMO free, and Kosher certified. - EXPERTISE & INDUSTRY LEADERSHIP: Our experts have been working with SAM-e (s-adenosylmethionine) and perfecting its formulation for over 2 decades. We are pleased to present a product that is backed by an incredible amount of science, literature, and research studies. - MOOD AND WELLBEING: SAM-e may help promote mood and well-being. - JOINT HEALTH: SAM-e may help maintain joint flexibility & mobility. - LIVER HEALTH: SAM-e may support healthy liver functions. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B079Z9XZRM | | Age Range Description | All Ages | | Best Sellers Rank | #3,056 in Health & Household ( See Top 100 in Health & Household ) #31 in Blended Vitamin & Mineral Supplements | | Brand | Nature's Trove | | Brand Name | Nature's Trove | | Container Type | Box | | Customer Reviews | 4.6 out of 5 stars 13,559 Reviews | | Dosage Form | Capsule | | Flavor | Unflavored | | Global Trade Identification Number | 00850056289061 | | Item Dimensions | 4.5 x 3.13 x 5.25 inches | | Item Form | Caplet | | Item Weight | 0.36 g | | Item dimensions L x W x H | 4.5 x 3.13 x 5.25 inches | | Manufacturer | Nature's Trove | | Manufacturer Part Number | TRSAM460X2 | | Material Features | GMO Free, Gluten Free, Kosher Certified, Vegan | | Number of Items | 2 | | Product Benefits | Bone & Joint Support, Liver Health Support | | Total Servings Per Container | 60 | | UPC | 850056289061 | | Unit Count | 120 Count | ## Product Details - **Age Range (Description):** All Ages - **Brand:** Nature's Trove - **Flavor:** Unflavored - **Item Form:** Caplet - **Item dimensions L x W x H:** 4.5 x 3.13 x 5.25 inches - **Number of Items:** 2 - **Package Information:** Box - **Product Benefits:** Bone & Joint Support, Liver Health Support - **Servings per Container:** 60 - **Unit Count:** 120 Count ## Images ![Nature's Trove SAM-e 400mg 120 Enteric Coated Caplets (2 Boxes of 60) - Vegan, Kosher, Non-GMO, Soy Free, Gluten Free - Mood and Joint Comfort - Cold Form Blister Packed - Image 1](https://m.media-amazon.com/images/I/81TkT02B9fL.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: What is the net yield of sam-e? 400 or 200mg? if 400mg s-adenosylmethionine tosylate disulfate then it is often a net yield of only 200mg-misleading!!** A: I ordered a bottle of Natures Trove Sam-e 400mg.When it arrived the first thing I noticed on the ingredients labeling was....SAM-E 400mg from 800mg of Sam-e Tosylate Disulfate... Hmmmm. I have always taken NatureMade Sam-e which states only ( Sam-e( S-adenosylmethionine 400mg. and found it excellent and stable. It has very good enteric coating and is consistent as to when I can feel it effecting my mood and energy. I know it is a reliable brand. I am going to give Natures Trove a fair shot as the price is better..... and hope that this difference in labeling of the main ingredient does not mean anything in reference to effectiveness. Does anyone have info to clarify the labeling? **Q: where is this made?** A: Hi, Nature's Trove SAM-e is made in the USA. **Q: Does this really contain titanium dioxide? (says it "might") that's toxic!!!** A: The ingredients are on the box and yes titanium dioxide is listed. Whether it is toxic or not I have no idea. Maybe in the amount that is contained in the product might determine whether it is or not. **Q: The front cover states its a natural deritive of yeast the back of the box says theres no yeast .I called the 1800 number to ask no answere?** A: Hi, SAM-e is derived from a specific natural chemical compound found in yeast however there is no yeast in this product. I hope that answers your question. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Fast and good source of nutritional supplements. *by M***M on July 15, 2020* SAMe, S-adenyl L Methionine has been noted by research to improve cartilage formation. As you see from the name, it is essentially an amino acid. I purchased the 200 and 400 mg quantities. The product is a molecule that is synthesized by some yeasts - bakers' yeast is most common. While I cannot personally double-blind test its effectiveness, scientific evaluation has, and has shown it to increase cartilage recovery. I nearly completely re-tore a long-previously reconstructed knee , and, as my other knee had also been damaged by significant aerial mistakes and landings I sought more than just the usual chondroitin, MSM, etc. Having seen live images of the cartilage damage in my knees, and exploring the research, I strongly feel that SAMe is worth purchase. This brand is naturally-sourced - a good selling point, and it is reasonably priced on comparison to many others. SAMe is also sold as neuroactive, due to its part in the synthesis of serotonin, which was a matter of concern. Serotonin is synthesized through the production and synthesis of this molecule, in great part by mutualist symbiotic enteric microorganisms. Again, because this is natural, it is almost certainly a good nutritional supplement, as enteric organisms tend to change quickly in response to different dietary intake. Thus, it promotes more regular synthesis of one of the most important neurotransmitters. Due to the highly stressful period in which all of us are immersed, I haven't looked deeper into that neurological issue, although we DO know a few things about it. Serotonin itself cannot cross into the brain, and that produced in the intestines affects other physiological processes - we need it. But excess serotonin production in the brain affects males and females differently and the brain's feedback processes tend to act to restore normality (it's possible that some individuals may experience persistent insufficiency OR excess, but those are a small minority. .If you suspect such long-term problem, do consult a medical therapist - Psychologists can refer those with metabolic problems of persistent types to psychiatrists who can test for such problems. But recognize that serotonin understanding is in its infancy, and the past with its SSRIs and other quite invasive drugging, is like using a hammer to fix a computer board or a brain) That, in short, is why I do NOT recommend that people seek neurotropic drugs - from alcohol to other drugs, we interfere with or destroy natural functioning, which it's sometimes better to address ONLY through physical, mental, social activities. SAMe is, though, pretty much methionine, a food, and we may often be deficient in that amino acid - which is why it can improve cartilage formation, as well as other variables like digestion. So, explore the effects of ANYTHING you ingest, and DO NOT just take things because of inane claims unsupported by rigorous scientific research. This company was extremely responsive (FAST!) to my Amazon order, and, so, with its component sourcing, seems a great place from which to purchase nutritional products. While I have experienced reduced pain , I had also been expanding the exercise of joints I injured and reinjured, and so cannot honestly evaluate sensations like pain reduction for others. I use less aspirin since the combination of SAMe, the natural healing process, and slow increase of exercise of affected joints, and as usual recommend any safe reduction of NSAID use. SAMe does not have the deleterious side effects of NSAIDs. ### ⭐⭐⭐⭐⭐ Works great for fibromyalgia! *by E***S on May 15, 2026* Great price and quality! ### ⭐⭐⭐⭐⭐ Better price than in store brands, and has helped me live a much happier life for years now. *by A***R on June 3, 2026* Once I saw that I've purchased this product 15 times, I thought I should probably write a review. I was diagnosed with depression many years ago, and was prescribed antidepressants which seemed to work at first but had a dulling effect over time. For me on antidepressants the world just became meh, no lows, no highs, just detached, and I hated that feeling. Sam-e has helped me be in the world, participate and feel much more normal. These help me enjoy life, even with all the craziness of it, especially in these times. Sam-e has absolutely improved my quality of life for many years now, and this is a trusted product of mine. ## Frequently Bought Together - Nature's Trove SAM-e 400mg 120 Enteric Coated Caplets (2 Boxes of 60) - Vegan, Kosher, Non-GMO, Soy Free, Gluten Free - Mood and Joint Comfort - Cold Form Blister Packed - Sports Research Triple Strength Omega 3 Fish Oil - Burpless Fish Oil Supplement w/EPA & DHA Fatty Acids from Single-Source Wild Alaskan Pollock - 1250 mg, 90 ct --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.com.eg/products/59482166-natures-trove-sam-e-400mg-120-enteric-coated-caplets-2](https://www.desertcart.com.eg/products/59482166-natures-trove-sam-e-400mg-120-enteric-coated-caplets-2) --- *Product available on Desertcart Egypt* *Store origin: EG* *Last updated: 2026-07-07*