Nutramax LaboratoriesDenamarin Liver Health Supplement for Medium Dogs - With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets

Vetri-Liver and Denamarin is working!!!My story: Our dog is a 12ish Jack Russell mix. In August 2017, he was off. Not himself. Bloodwork and ultrasound showed he likely had Chronic Hepatitis. Put him on Denamarin. Bloodwork improved, but still not perfect. Had the vet do a dental thinking that the liver issues could be from bad teeth. They put him on a preventative antibiotic. 1 week after the Dental he spiked a 106 fever. He was ultimately put on IVs with a different antibiotic. Fever came down, felt better. Noticed that he had developed a licking issue after eating which was new. Fever slowly started to climb back upward. At 104 he was put back on IVs, taken off of all antibiotics in an attempt to get the bacteria to flourish and to isolate it. The only problem was that once he was off of the antibiotics his temperature went normal never to return. Eating throughout this has been difficult. Turning down filet mignon or whatever concoction I could come up with to tempt him to eat. I had pointed out to the vets (lots of them) that the antibiotics warned against liver and kidney issues. Everyone poo poo'd that. Well, it turns out that his liver couldn't process them.I took him home on Christmas Day from the vet hospital. They wanted to do a liver biopsy, but I rejected it. He already looked like warmed over death. Wasn't eating a thing in the hospital. They would have had to put him back on antibiotics. - And there was no clear indication that the liver was the origin of the problem, and could just be a secondary to another issue like heart disease (he does have a small heart murmur, but his heart is working sufficiently), cancer, etc. Even if we knew exactly what the liver diagnosis was, the treatment wouldn't be much different: Diet, supplements and potentially prednisone (which is hard on the liver as well - catch 22)At home, he was a new dog. He started eating. I researched every liver diet, and started with a very bland, home-cooked meal. I noticed that if I added a hi-end kibble to his diet, there would be more licking (licking surfaces like the carpeting). I read where compulsive licking is often intestinal distress. I'm not convinced that he also didn't have some kind of gastric issue, like gastric ulcers, or other intestinal issue, perhaps because of the liver or maybe even driving the liver problem.It is the end of April 2018, and he is doing well. I started him on Vetri-liver in the AM a couple of months ago with a breakfast of eggs, cottage cheese, oatmeal, rice, and chicken/turkey or beef). The Vetri-liver isn't extremely palatable, but I just cut it in pieces and put it in meat or cheese, and it will go down. Since I don't have a firm diagnosis for the liver problem, I looked for zinc and anti-oxidants to help the liver even if he had a copper retention problem. Zinc is supposed to offset copper in your diet. It also has some other supplements that he may need.Afternoon, he gets his Denamarin tablet (2 hours after the last meal) and 1 hour before dinner.Supposedly vegetable protein is better for dogs with liver disease. So I came up with some treats that also helped, especially in the beginning when getting him to eat was hard. I fill a turkey pan with: eggs, meat, carrots, sweet potatoes, tofu, wheat germ, peanut butter, coconut oil, and enough oats and a little bit of flour to make a cookie dough. The secret ingredient is a little bacon grease and bacon for palatability. Yes, bad, but makes the difference between this going down the hatch. These can be a mid-day snack, or actually a small meal if we are out hiking, etc. I bake them on cookie tins like brownies, cut them into squares, put them in baggies, and throw them in the freezer. This way they stay fresh.Dinner is rice/oatmeal/sweet potatoes/pumpkin or yams mixed with eggs/chicken/turkey/beef along with some well-processed veggies.I'm not convinced that I'm feeding a balanced diet, so I bought some senior dog vitamins that he gets periodically.Slowly the weight is coming back on. Exercise is important, because he is hungry after exercise. So a small walk in the morning before breakfast and walk before dinner really makes a difference with the pills and food going down. As long as he is eating soft, smaller meals, the compulsive licking has stopped.He is energetic, playing with toys, bright on his walks and back among the living. His liver enzymes are not perfect: ALT started at 275 (August 2017), went to 1,800 during the antibiotic reaction and spiked fever, back to 275 and now down to 253 most recently. ALP started at 263, 656 at its worst, and now at 167. I don't know if I will be successful in getting them to normal ranges, but if I look at his quality of life, it looks pretty good now.I wanted to share my story, because you don't hear often that antibiotics could almost kill your dog. And.....your dog can come back after refusing to eat anything after dire illness.Considering a backpack Trip!!

I have 2 dogs taking this: it is cheaper than at the Vet office and delivered to my front door. So far it is helping their liver values.

Before I review the actual product, I have to complain about the sudden price hike, last week this product was $39 now it's gone up to $49?? I only bought it on Amazon because it was cheaper than my vet, not anymore! Plus, what's with the 1 - 2 months before shipping? I'm able to get this at several vets in my area, one sells it for around $40., buying it for the same price with free shipping on Amazon was a simple convenience.Anyway, my dog takes high dose steroids, his liver levels where high among other problems. Medications like steroids and seizure meds will effect the liver function and long term these meds will eventually cause liver failure. An ER vet gave these to him one night and ever since then my dog has been doing great, these really helped him get back to normal! I've had his liver function tested several times since he started these and the levels have been perfect with the exception of one slight elevation that is to be expected with steroid use! My dog has a digestive disease and getting his liver and protein level back to normal was very important to help manage his disease, if the levels are not right he is very ill, I feel that these supplements helped my dog get back to normal which in turn helped him to gain back the weight he had lost. I honestly thought he wasn't going to live more than a month or two, he was looking really bad. I started him on these and stuck with his normal healthy diet and he bounced right back and has stayed that way.Look around though, the prices vary everywhere, I wouldn't spend more than $40.on them.UPDATE: I see they dropped the price again, back to $37, that's better. Not sure why the price fluctuates so much! Still would like to be able to get it when I need it though, waiting months isn't ideal.Another update on price; If you wait a minute the price will either go up or drop. Today I almost ordered some more, tonight the price has gone up again.. several times a day this price is changing, I don't get it. But watch for $40. that is the average low price but they have been cheaper.

I've been using this for a while now, and the liver health support it provides is impressive. My dog was noticeably better after just a few days, and his bloodwork improved significantly after a month. This supplement has genuinely made a world of difference for my pet's health and well-being. Highly recommended!

I give this to my dog and he's doing great. For one this is cheaper than purchasing at the vet office. However, for my needs and situation I need to make sure i purchase things of good quality and reasonable prices for such a time as this.

This medicine stated 13-34 lb dogs, we have been buying this medication for a long time!, the color of the pill should be blue!!!, the box we bought the color of the pills were pink!, we are scared to give this to our dog, my husband threw the pill away .

My vet recommended me giving my 12 year old and 17 pound fur-baby Denamarin with SAMe. She stated it was important that the liver supplement contained SAMe, and she assured me that his liver enzyme levels would improve. I read a lot of reviews that said the pet owners were having issues getting their dog to take the supplement. I also tried giving my puppy other Nutramax vitamins in chewable or powder form that I had to throw away because he just would not eat the chewables or eat his food after adding powder to it. I opted to purchase this supplement in a blue coated tablet form and I AM GLAD I DID. My puppy is swallowing the pill with no problem. I can't say that it has improved his levels yet, but I can say I am able to give it to him with no issues on an empty stomach without altering the tablet form. Hooray!

Amazon's price on this medication for my dog is the best I can find in my area.