Nature's Trove SAM-e 400mg 120 Enteric Coated Caplets (2 Boxes of 60) - Vegan, Kosher, Non-GMO, Soy Free, Gluten Free - Mood and Joint Comfort - Cold Form Blister Packed

SAMe, S-adenyl L Methionine has been noted by research to improve cartilage formation. As you see from the name, it is essentially an amino acid. I purchased the 200 and 400 mg quantities. The product is a molecule that is synthesized by some yeasts - bakers' yeast is most common. While I cannot personally double-blind test its effectiveness, scientific evaluation has, and has shown it to increase cartilage recovery. I nearly completely re-tore a long-previously reconstructed knee , and, as my other knee had also been damaged by significant aerial mistakes and landings I sought more than just the usual chondroitin, MSM, etc. Having seen live images of the cartilage damage in my knees, and exploring the research, I strongly feel that SAMe is worth purchase. This brand is naturally-sourced - a good selling point, and it is reasonably priced on comparison to many others. SAMe is also sold as neuroactive, due to its part in the synthesis of serotonin, which was a matter of concern. Serotonin is synthesized through the production and synthesis of this molecule, in great part by mutualist symbiotic enteric microorganisms. Again, because this is natural, it is almost certainly a good nutritional supplement, as enteric organisms tend to change quickly in response to different dietary intake. Thus, it promotes more regular synthesis of one of the most important neurotransmitters. Due to the highly stressful period in which all of us are immersed, I haven't looked deeper into that neurological issue, although we DO know a few things about it. Serotonin itself cannot cross into the brain, and that produced in the intestines affects other physiological processes - we need it. But excess serotonin production in the brain affects males and females differently and the brain's feedback processes tend to act to restore normality (it's possible that some individuals may experience persistent insufficiency OR excess, but those are a small minority. .If you suspect such long-term problem, do consult a medical therapist - Psychologists can refer those with metabolic problems of persistent types to psychiatrists who can test for such problems. But recognize that serotonin understanding is in its infancy, and the past with its SSRIs and other quite invasive drugging, is like using a hammer to fix a computer board or a brain) That, in short, is why I do NOT recommend that people seek neurotropic drugs - from alcohol to other drugs, we interfere with or destroy natural functioning, which it's sometimes better to address ONLY through physical, mental, social activities. SAMe is, though, pretty much methionine, a food, and we may often be deficient in that amino acid - which is why it can improve cartilage formation, as well as other variables like digestion. So, explore the effects of ANYTHING you ingest, and DO NOT just take things because of inane claims unsupported by rigorous scientific research. This company was extremely responsive (FAST!) to my Amazon order, and, so, with its component sourcing, seems a great place from which to purchase nutritional products. While I have experienced reduced pain , I had also been expanding the exercise of joints I injured and reinjured, and so cannot honestly evaluate sensations like pain reduction for others. I use less aspirin since the combination of SAMe, the natural healing process, and slow increase of exercise of affected joints, and as usual recommend any safe reduction of NSAID use. SAMe does not have the deleterious side effects of NSAIDs.

Great price and quality!

Once I saw that I've purchased this product 15 times, I thought I should probably write a review. I was diagnosed with depression many years ago, and was prescribed antidepressants which seemed to work at first but had a dulling effect over time. For me on antidepressants the world just became meh, no lows, no highs, just detached, and I hated that feeling. Sam-e has helped me be in the world, participate and feel much more normal. These help me enjoy life, even with all the craziness of it, especially in these times. Sam-e has absolutely improved my quality of life for many years now, and this is a trusted product of mine.

Works like the more expensive brand I was taking. The blister packs are great for freshness and tracking. This is the 2nd time I've ordered it and I plan to continue to use this brand

This is the 2nd time I've ordered it. No after taste, I'm in a much better mood state when I take it and my knee joint feels more lubricated and less achy.

Great price and great quality

Since losing my insurance Sam-e has given me the ability to reduce my depressive concerns with less side effects I take additional supplements and im feel better as a result of going this way.

Excellent choice, effectiveess

mejor precio en este caso

Mi esposa es la que va empezar a tomarlas, se las recomendaron,

se necesita mas tiempo a saber si esta funcionando o no